Development of Next Generation Dynamic Cell Culture Model:
3D Microfluidic Magnetic Cell Culture
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MNP Research Group
The MNP research group is currently working on fluorescent micro/nanoparticle synthesis, drug discovery-toxicity testing kits for point-of-care and target delivery, antimicrobial materials, and microfluidic water treatments with two ongoing projects. The research interests focused on green synthesis techniques, hybrid particles, and 3D cell culture models. Our contributions appeared in peer-reviewed journal articles, patents, and projects. We collaborate with several universities and industrial partners around the world.
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MNP Research Group
Magneto-electrochemical biosensing for pathogen detection using nuclease-responsive nanohybrids
The development of sustainable and highly sensitive diagnostic platforms is critical for rapid pathogen identification and effective disease management. Here, a green, magneto-electrochemical biosensing strategy is reported for the selective detection of Streptococcus pneumoniae based on pathogen-specific nuclease activity. Uniform organic–inorganic hybrid polyhedral oligomeric silsesquioxane (POSS) nanoparticles were synthesized via an ultrafast…
Multifunctional POSS-based nanoparticles functionalized with silver, SPIONs, and rhamnolipid for antibacterial applications
Nano-engineered materials, particularly those featuring bio-based surface modifications, are emerging as effective tools in combating bacterial infections. In this study, polyhedral oligomeric silsesquioxane (POSS) nanoparticles were functionalized with silver nanoparticles (Ag), superparamagnetic iron oxide nanoparticles (SPIONs), and the biosurfactant rhamnolipid (RL)—either individually or in combination—to evaluate their antibacterial and antibiofilm…
Ultrafast Green Synthesis of Superparamagnetic Hybrid Nanoparticle for Advanced Applications
The integration of superparamagnetic iron oxide nanoparticles (SPIONs) into functional hybrid nanostructures remains a challenge, particularly in preserving their magnetic properties within composite frameworks. Herein, we present a rapid and environmentally friendly synthesis strategy for SPION- decorated polyhedral oligomeric silsesquioxane (POSS) nanoparticles. The process involves UV- induced polymerization to form…
Magneto-electrochemical biosensing for pathogen detection using nuclease-responsive nanohybrids
The development of sustainable and highly sensitive diagnostic platforms is critical for rapid pathogen identification and effective disease management. Here, a green, magneto-electrochemical biosensing strategy is reported for the selective detection of Streptococcus pneumoniae based on pathogen-specific nuclease activity. Uniform organic–inorganic hybrid polyhedral oligomeric silsesquioxane (POSS) nanoparticles were synthesized via an ultrafast…
Multifunctional POSS-based nanoparticles functionalized with silver, SPIONs, and rhamnolipid for antibacterial applications
Nano-engineered materials, particularly those featuring bio-based surface modifications, are emerging as effective tools in combating bacterial infections. In this study, polyhedral oligomeric silsesquioxane (POSS) nanoparticles were functionalized with silver nanoparticles (Ag), superparamagnetic iron oxide nanoparticles (SPIONs), and the biosurfactant rhamnolipid (RL)—either individually or in combination—to evaluate their antibacterial and antibiofilm…
Ultrafast Green Synthesis of Superparamagnetic Hybrid Nanoparticle for Advanced Applications
The integration of superparamagnetic iron oxide nanoparticles (SPIONs) into functional hybrid nanostructures remains a challenge, particularly in preserving their magnetic properties within composite frameworks. Herein, we present a rapid and environmentally friendly synthesis strategy for SPION- decorated polyhedral oligomeric silsesquioxane (POSS) nanoparticles. The process involves UV- induced polymerization to form…