Development of Next Generation Dynamic Cell Culture Model:
3D Microfluidic Magnetic Cell Culture
Wellcome!
MNP Research Group
The MNP research group is currently working on fluorescent micro/nanoparticle synthesis, drug discovery-toxicity testing kits for point-of-care and target delivery, antimicrobial materials, and microfluidic water treatments with two ongoing projects. The research interests focused on green synthesis techniques, hybrid particles, and 3D cell culture models. Our contributions appeared in peer-reviewed journal articles, patents, and projects. We collaborate with several universities and industrial partners around the world.
Thanks for your interest!
citation
article
Project done
Research Applications
Separation Systems
Bioprocessing and Chromatography:
• Bioseparation techniques for the purification of proteins, antibodies, and other biopharmaceuticals.
• Continuous bioprocessing methods for increased efficiency and productivity.
• Liquid Chromatography (HPLC): High-performance liquid chromatography is widely employed to separate biomolecules based on various properties.
Nanotechnology in Separation:
• Application of nanomaterials in separation processes for enhanced selectivity and efficiency.
• Nanofluidic devices for precise control in separation at the nanoscale
Cell Culture
Cell Culture Techniques:
• Monolayer Culture: Cells adhere to the substrate and form a single layer.
• 3D Culture: Mimics the in vivo environment, promoting more natural cell behavior.
• Dynamic Culture: Cells are exposed to controlled mechanical forces and shear stress.
Drug Discovery:
• Screening and testing potential drugs before moving to in vivo studies,
• Evaluate the toxicity of chemicals and drugs, reducing the need for animal testing.
Catalyst
Heterogeneous Catalysts:
• Supported Noble Metal Catalysts: Palladium (Pd), platinum (Pt), and other noble metals are supported on various materials like activated carbon for catalytic reduction of contaminants.
Biosensors
Surface-enhanced Raman scattering (SERS)
• the enhanced signals provided by nanostructured metallic surfaces
• Offers high sensitivity and specificity for detecting and identifying biological molecules
Research Interest
MNP research group
Polymer Particles
Monodisperse polymeric particles
• Microparticles from 1µm to 10µm in size with different functional groups (carboxyl, amin, hydroxyl, zwitterionic …)
Hybrid Particles
• Polymer-Metal Hybrids
• Polymer-Inorganic Nanoparticle Hybrids
• Lipid-Polymer Hybrids
Lipid Particles
• Solid lipid nanoparticles (SLNs)
• Nanostructured lipid carriers (NLCs)
• Lipid nanoparticles (LNPs)
Magnetic Particles
• Superpara magnetic iron nano oxides (SPION) particles
• Magnetic nanoparticle decorations
Metal Particles
• Gold nanoparticles
• Silver nanoparticles
Janus Particles
• Magnetic and fluorescent janus particles
Our Latest News
MNP Research Group
Multifunctional POSS-based nanoparticles functionalized with silver, SPIONs, and rhamnolipid for antibacterial applications
Nano-engineered materials, particularly those featuring bio-based surface modifications, are emerging as effective tools in combating bacterial infections. In this study, polyhedral oligomeric silsesquioxane (POSS) nanoparticles were functionalized with silver nanoparticles (Ag), superparamagnetic iron oxide nanoparticles (SPIONs), and the biosurfactant rhamnolipid (RL)—either individually or in combination—to evaluate their antibacterial and antibiofilm…
Ultrafast Green Synthesis of Superparamagnetic Hybrid Nanoparticle for Advanced Applications
The integration of superparamagnetic iron oxide nanoparticles (SPIONs) into functional hybrid nanostructures remains a challenge, particularly in preserving their magnetic properties within composite frameworks. Herein, we present a rapid and environmentally friendly synthesis strategy for SPION- decorated polyhedral oligomeric silsesquioxane (POSS) nanoparticles. The process involves UV- induced polymerization to form…
Recent Developments and Applications in Two-Dimensional and Three-Dimensional Cell Culture Models
The limited availability of resources written in Turkish in our field negatively affects both academic research and sectoral developments. In an effort to partially address this gap, the article we have written aims to serve as a guide for both researchers interested in the subject and practitioners. 📄For readers interested…
Multifunctional POSS-based nanoparticles functionalized with silver, SPIONs, and rhamnolipid for antibacterial applications
Nano-engineered materials, particularly those featuring bio-based surface modifications, are emerging as effective tools in combating bacterial infections. In this study, polyhedral oligomeric silsesquioxane (POSS) nanoparticles were functionalized with silver nanoparticles (Ag), superparamagnetic iron oxide nanoparticles (SPIONs), and the biosurfactant rhamnolipid (RL)—either individually or in combination—to evaluate their antibacterial and antibiofilm…
Ultrafast Green Synthesis of Superparamagnetic Hybrid Nanoparticle for Advanced Applications
The integration of superparamagnetic iron oxide nanoparticles (SPIONs) into functional hybrid nanostructures remains a challenge, particularly in preserving their magnetic properties within composite frameworks. Herein, we present a rapid and environmentally friendly synthesis strategy for SPION- decorated polyhedral oligomeric silsesquioxane (POSS) nanoparticles. The process involves UV- induced polymerization to form…
Recent Developments and Applications in Two-Dimensional and Three-Dimensional Cell Culture Models
The limited availability of resources written in Turkish in our field negatively affects both academic research and sectoral developments. In an effort to partially address this gap, the article we have written aims to serve as a guide for both researchers interested in the subject and practitioners. 📄For readers interested…